Endocrine Abstracts

A 50 year old Asian lady developed neck pain and sore throat 10 days after first dose of AstraZeneca COVID-19 vaccination. Her dentist thought she had tonsillitis. She then presented to hospital a few days later with dyspnoea, palpitations, tremor and neck pain. She was apyrexial but clinically thyrotoxic with sinus tachycardia. Thyroid gland had normal size with tenderness without bruit or lymphadenopathy. Her Free T4 was >100 pmol/l (11.2 - 20.2), TSH < 0.01mIU/l, ES...

27 years old lady with recurrent Graves’ thyrotoxicosis for 5 years delivered her baby uneventfully and her thyrotoxicosis worsened 2 months after pregnancy when her FT4 bounced back up to 38 pmol/l (12–22) so her propylthiouracil (PTU) was increased from 200 to 400 mg. Despite of continuing high dose of PTU for few months she remained thyrotoxic and became neutropenic [Neutrophil 0.67×109 (2–7)], decision was made to proceed with thyroidectomy b...

Case history: 36 years old, 14 weeks pregnant lady was referred to endocrinology department by GP urgently with corrected Calcium CCa of 2.97 mmol/l and normal parathyroid hormone (PTH). Her symptoms were urinary frequency and nausea. She had 3 previous miscarriages and 2 normal births. She was on folic acid and vitamin D supplements. There was family history of type 2 diabetes and B12 deficiency. Her 6 family members had normal calcium levels.Investigat...